With all the attention it has received over the past decade, you’ve likely heard people talking, perhaps incessantly at times, about the benefits of CBD. It’s true—CBD is remarkable for many applications. However, it’s just one of over 100 cannabinoids found in hemp and cannabis plants! Let’s dive into CBD, as it absolutely deserves attention, but I also want to highlight some lesser-known cannabinoids and their potential benefits.

CBD

CBD is the granddaddy of all fully legal cannabinoids. It burst onto the scene following the story of Charlotte Figi, whose mother used a high-CBD oil extracted from a cannabis strain called “Hippie’s Disappointment” to treat her daughter’s severe seizures. This low-THC, high-CBD oil produced miraculous effects; Charlotte went from experiencing over 300 seizures a day to just a few per month. “Hippie’s Disappointment” was later renamed “Charlotte’s Web,” and high-CBD varieties are now widely available in dispensaries.

You might be wondering, “That’s interesting, but what can CBD do for me?” The answer is quite a lot. Numerous published studies provide substantial evidence of CBD's effectiveness in reducing chronic pain, surgical pain, nerve pain, and inflammation. When combined with other cannabinoids like delta-9 THC, its effects could be even more pronounced.

CBD is also showing great promise in mental health. Research indicates that CBD can help manage social anxiety, depression, insomnia, PTSD, and everyday stress. Additionally, it shows potential in treating conditions such as multiple sclerosis, dementia, and Alzheimer’s disease.

High CBD Strains: Harlequin, ACDC, Cannatonic, Pennywise

CBN

Next on our cannabinoid countdown is Cannabinol (CBN). Found only in trace amounts in cannabis flowers, CBN is mildly psychoactive and is produced as THC oxidizes and ages, often present in older buds. While many believe CBN induces sedation, research suggests it works best for sleep when combined with THC and/or CBD. CBN also shows promise as a pain reliever and anti-inflammatory. Notably, it has been identified as an effective antibacterial agent, even against resistant strains like MRSA. Preliminary studies suggest that CBN may serve as a neuroprotector, potentially delaying the onset of ALS and other neurodegenerative conditions. Additionally, CBN is being explored for its appetite-stimulating properties, which could benefit patients needing to increase their appetite without the euphoric effects of THC.

High CBN Strains: Bubble Gum, Durban Poison, Death Star

CBC

Cannabichromene (CBC) is another powerhouse cannabinoid. It interacts with multiple pain pathways at the spinal level and offers anti-inflammatory benefits that may provide relief for conditions like osteoarthritis. CBC's anti-inflammatory properties have even been shown to reduce sebum production and inflammation associated with acne. One of its most promising benefits is its potential as a cancer-fighting compound; studies dating back to 2006 have demonstrated CBC’s ability to inhibit tumor growth. Additionally, CBC supports mental health by helping combat depression and maintaining the health of brain cells, which can protect against neurological diseases.

High CBC Strains: Purple Cadillac, Bubba Cookie, Sour Tsunami

CBG

Cannabigerol (CBG) shares some antibacterial and appetite-stimulating qualities with CBN but also offers unique benefits. It shows promise for those suffering from inflammatory conditions like ulcerative colitis and IBD due to its anti-inflammatory properties. Recent studies suggest CBG could be beneficial for anxiety and depression, as it appears to inhibit GABA reuptake. CBG may also help glaucoma patients by reducing intraocular pressure. Most impressively, laboratory studies indicate that CBG can block receptors that promote the growth of cancer-causing cells. While more research is needed, these initial findings are compelling and underscore the importance of further studies.

High CBG Strains: White CBG, Stem Cell, Super Glue CBG

THC-V

THC-V (tetrahydrocannabivarin) is a lesser-known cannabinoid that is gaining attention for its unique properties and potential health benefits. Unlike its more famous and similarly named cousin THC, THC-V has a distinct profile that may offer a range of therapeutic advantages. It is often described as having an appetite-suppressing effect, making it a potential ally for those looking to manage their weight or reduce food cravings. Additionally, THC-V may possess anti-inflammatory properties and show promise in managing conditions such as diabetes by helping to regulate blood sugar levels. Preliminary studies also suggest that THC-V could play a role in anxiety reduction and pain relief, though more research is needed to fully understand its effects. As interest in cannabis research expands, THC-V stands out as a cannabinoid with exciting potential for both medicinal and recreational use.

As research continues to progress and the world of cannabinoids continues to expand, it’s clear that CBD is just the tip of the iceberg. With cannabinoids like THC-V, CBN, CBC, and CBG offering promising health benefits, there’s a vast potential for improving quality of life across various conditions. As research evolves, we can expect to uncover even more about these compounds and how they can be integrated into our wellness routines. Whether you're seeking relief from pain, support for mental health, or even appetite stimulation, exploring the alphabet soup of cannabinoids could lead to new avenues for health and well-being. So, as you consider your options, remember that the therapeutic potential of these lesser-known cannabinoids is worth investigating.